Which radiopharmaceutical is used for spleen imaging?

• A. Tc HMPAO
• B. Tc RBCs
• C. Tc MDP
• D. Tc DTPA

Answer: (B)

The use of Technetium-labeled red blood cells (Tc RBCs) is particularly well-suited for spleen imaging due to their ability to be sequestered by the spleen, which plays a vital role in filtering and recycling red blood cells. The spleen's highly vascular nature allows for efficient uptake of these labeled cells, providing clear and functional imaging of the organ.

In this context, the other options serve different purposes. Technetium HMPAO is utilized primarily for brain perfusion imaging, Tc MDP is utilized for bone imaging, and Tc DTPA is often used for kidney function imaging. None of these alternatives are designed specifically for visualizing the spleen, which highlights the unique utility of Tc RBCs in this specific application. The binding affinity of the labeled red blood cells for splenic tissue ensures accurate assessment of spleen size, shape, and overall function, making it the preferred choice for spleen imaging.