What is the primary indication for a Tc mebrofenin scan?

• A. Cardiac imaging
• B. Hepatobiliary imaging for gallbladder function
• C. Bone marrow imaging
• D. Brain perfusion imaging

Answer: (B)

The primary indication for a Tc mebrofenin scan lies in its use for hepatobiliary imaging, particularly in assessing gallbladder function. Tc mebrofenin is a radiopharmaceutical that is specifically designed to evaluate hepatic (liver) uptake and biliary excretion. Upon administration, this tracer is taken up by hepatocytes (liver cells) and subsequently secreted into the bile, allowing for the visualization of the hepatobiliary system.

In clinical practice, the use of Tc mebrofenin can help diagnose conditions such as acute cholecystitis, where gallbladder function is compromised. By observing whether the gallbladder is visualized on the scan, medical professionals can determine if the organ is functioning properly or if there is an obstruction preventing normal bile flow.

The other indications, while relevant in their respective contexts, do not pertain specifically to the function or condition of the gallbladder as Tc mebrofenin does. Cardiac imaging typically employs different agents that are more suited for assessing myocardial perfusion. Bone marrow imaging uses radiopharmaceuticals focused on the skeletal system or hematopoietic activity. Brain perfusion imaging generally involves tracers that highlight cerebral blood flow rather than hepatobiliary function