What is the administration method for Tc HMPAO tagged WBCs?

• A. Subcutaneous injection
• B. Oral ingestion
• C. Inhalation
• D. IV

Answer: (D)

The administration method for Tc HMPAO tagged white blood cells (WBCs) is intravenous (IV). This method is preferred because it allows for the direct introduction of the radiopharmaceutical into the bloodstream, ensuring that the labeled cells can circulate and reach the sites of infection or inflammation effectively. The intravenous route is also essential in nuclear medicine imaging to achieve a quick distribution of the radiolabeled cells and obtain accurate diagnostic results.

Other methods, such as subcutaneous injection or oral ingestion, would not provide the same level of effectiveness for the visualization of internal processes, as they could lead to reduced bioavailability of the radiopharmaceutical or cause localized effects that do not represent the systemic condition under evaluation. Inhalation is not applicable in this context as tagged white blood cells are intended for systemic assessment rather than respiratory purposes.