How is Tc bicisate (ECD) usually administered?

• A. Orally
• B. Intradermally
• C. Intramuscularly
• D. Intravenously

Answer: (D)

Tc bicisate, also known as ECD (ethyl cysteinate dimer), is typically administered intravenously. This route of administration is essential because it allows for rapid distribution of the radiopharmaceutical throughout the bloodstream, enabling effective imaging of the brain in nuclear medicine studies. Intravenous administration ensures that the technetium-labeled compound reaches the regions of interest quickly and provides clear imaging results, particularly for brain perfusion studies and assessing conditions like stroke or epilepsy.

The intravenous route also minimizes the potential for altering the pharmacokinetics of the compound, which can be critical for accurate diagnostic imaging. In contrast, other routes such as oral or intramuscular would not provide the same rapid and direct access to systemic circulation, making them inappropriate for the intended diagnostic applications of Tc bicisate (ECD).